The Pharmaceutical industry in India is the world’s third-largest in terms of volume and 10th largest in value terms. According to the department of pharmaceuticals, India, the total turnover of India’s pharmaceuticals industry between 2008 and September 2009 was US$21.04 billion. The Indian market is expected to grow to the level of $50bn by 2020.India is now among the top five pharmaceutical emerging markets of the world. India’s drugs and pharmaceuticals industry is expected to grow at a compound annual growth rate (CAGR) of 14 per cent to reach a turnover of $ 47.06 billion by 2018.
Indian pharmaceutical industry is gaining rapid popularity owing to the rise in the Bulk Drug Intermediates Manufacturers. There are many manufacturers which produce a package of the drug intermediates exported outside India to a variety of pharmaceutical chemical industries. While there are a plenty of rising pharmaceutical intermediates industrial areas emerging all over India, Vadodara, Gujarat is one of the main hub for bulk drug manufacturing. Various pharma intermediates like Hexamethyl Disiloxane (HMDSO), Trimethyl Chlorosilane (TMCS ), Hexamethyl Disilazane ( HMDS / HMDZ ) Chloromethyl Isopropyl Carbonate (CMIC ).
Hexamethyl Disiloxane (HMDSO) CAS NO. : 107-46-0, is a specialty chemical, which has variety of applications. An organosilicon compound in nature, it is highly volatile. It is a colorless and clear liquid and is mainly used as a reagent and solvent in the process of organic synthesis. HMDSO can be prepared by the hydrolysis of trimethylsilyl chloride.
Trimethyl Chlorosilane (TMCS) CAS NO. : 75-77-4, is used in the manufacture of all types of silicon compounds. It is also useful in the preparation of alkylation agent and is also used in the creation of drugs nad medicines. Moreover, when this pharma intermediate reacts with alchohol, it can be widely used for the manufacturing of anhydrous solutions of HCL in alcohols that can be subsequently used in synthesis if suitable esters from nitriles and carboxylic acids.
Hexamethyldisilazane (HMDS), CAS No. : 999-97-3, which is also known as HMDS, is a special organosilicon compound that is a derivative of ammonia. HMDS has many uses as a chemical intermediate, release agent, lubricant, coupling agent, deactivator for chromatographic support materials, silylating agent in pharmaceuticals, adhesion promoter for photoresists on silicon (electronics), as reagent for temporary protection of reactive sites in manufacture of betalactum antibiotics, etc.
Chloromethyl isopropyl carbonate (CMIC) CAS NO. : 35180-01-9, have revolutionalized the field of pharma intermediates by being the primary part in the manufacturing tenofovir, a proven cure for AIDS.
The rising specialty and pharma intermediates industry in Vadodara include HMDSO, CMIC, TMC, and HMDS Manufacturers. Chemcon Speciality Chemicals Pvt. Ltd. is one such Vadodara based company which excels in the manufacture of the above chemicals. Chemcon have a widely appreciated range of drug intermediates which have been acclaimed not only in the domestic market but also internationally.