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Hexamethyl Disiloxane – Sustainable Rise in the Demand of Pharmaceutical Ingredients

Hexamethyl Disiloxane is one of the most significant pharmaceutical ingredients catering to the demand of the pharma industry. Chemcon Specialty Chemicals has been focusing on manufacturing quality chemicals like HMDS so that they can be used in manufacturing processes with great ease. This clear and colorless liquid named HMDSO has a molecular formula C6H18OSi2. The boiling range for HMDSO is 101° C – 104° C and its purity as per GC is NLT 99.00 %.

Hexamethyl Disiloxane is a specialty chemical which is causing a huge stir in the industry, due to the various purposes it serves. It is basically an organosilicon compound which is volatile in nature. This colorless and clear liquid is mainly used as a reagent and solvent in the process of organic synthesis. HMDSO is prepared through trimethylsilyl chloride’s hydrolysis. This chemical is also used in the form of an internal standard meant for standardizing the chemical shift in spectroscopy of 1H NMR. However, an important thing that makes HMDSO really important in the industry is the fact that it is usually used for crystallizing compounds which are highly lipophilic in nature. In the pharmaceutical industry, it is used to prepare liquid bandages so that they can protect your skin from irritation when it has been badly damaged.

Hexamethyldisiloxane-HmdsoHexamethyl disiloxane’s plasma polymerization for the purpose of humidity sensing application is also a well known phenomenon. All the humidity sensitive layers that are derived from pure Hexamethyl Disiloxane Manufacturer are evaluated and studied thoroughly. The popular sensing properties including the relative humidity are also examined. HMDSO thin films display a small recovery and response of around 34 and 8 s for desiccation and humidification processes, respectively along with extremely low hysteresis. In many other fields, hexamethyl disilazane has proved to be an integral part of the manufacturing process.

HMDSO is used across the world for crystalling the compounds which are highly lipophilic in nature. This is mainly due to the fact that this pharma intermediate has poor solvating power. It is also employed majorly in liquid bandages and cavilon spray, which in turn helps in safeguarding damaged human skin from any harmful infections and irritation. HMDSO has even been used as a major reporter molecular for measuring any kind of (Po2).

Safety requirements

While handling HMDSO in your manufacturing unit, you’ll have to make sure that you keep all the below mentioned safety requirements handy.

•    Eyeshields
•    Faceshields
•    Full-face respirator
•    Gloves
•    Respirator cartridge

Thus, it can be easily concluded that hexamethyl disiloxane has contributed significantly to the pharma intermediate industry lately.